In vivo, cells live, migrate and invade in 3D. GradientEZ is a qualitative cell migration and invasion assay that allows cells to migrate and invade in 3D.
In a human body, migrating and invading cells also make directional decisions in response to multiple stimuli coming from various directions.
GradientEZ enables to model such signaling in vitro in a single well. Add cells to the center and test multiple modulators of cell motility or invasion by adding them to petals or lobes.